You don't aim at the Moon.
You aim at where it's going to be.
Orion orbits Earth in a circle — the same orbit from Part 1. The Moon orbits too, further out, much slower.
The BOOST fires a burst of speed in the direction Orion is already moving. This stretches the circular orbit into a long ellipse — like pulling a rubber band.
The trick is timing. The boost always adds the same speed. But the ellipse shoots out in whatever direction Orion is heading at that moment. If the Moon happens to be there when the ellipse arrives — you're going to the Moon.
If not — you've launched into empty space. Lost.